Immunoassay and test kit for thrombin-antithrombin iii complex

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 21/08 (2006.01) C07K 16/40 (2006.01) G01N 33/573 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2137785

The present invention provides an immunoassay for thrombin-antithrombin complex in a human fluid sample. The assay comprises reaction of a human fluid sample with at least two antibodies or immunoreactive fragments thereof, wherein at least one of the antibodies binds to thrombin-antithrombin III complex in the sample, but exhibits essentially no cross-reactivity with antithrombin III and complexes of antithrombin III with other serine proteaste factors.

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