Immunoassay for identifying alcoholics and monitoring...

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 14/79 (2006.01) C07K 16/18 (2006.01) C12N 5/18 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01) G01N 33/98 (2006.01)

Patent

CA 2119651

The invention provides an antibody which reacts selectively with a transferrin homolog found in alcoholics but not in non-alcoholics. The invention also provides methods of making the antibody and hybridomas producing the antibody. Finally, the invention provides an immunoassay which utilizes the antibody to detect or quantitate the alcoholic transferrin homolog and a kit for an immunoassay which comprises a container of the antibody.

L'invention décrit un anticorps qui réagit sélectivement avec un homologue de la transferrine que l'on trouve chez les alcooliques mais pas chez ceux qui ne le sont pas. L'invention décrit également des procédés pour fabriquer un anticorps et des hybridomes produisant ce dernier. Enfin, l'invention décrit un dosage immunologique qui utilise l'anticorps pour détecter ou quantifier l'homologue de la transferrine chez les alcooliques, ainsi qu'une trousse de dosage immunologique contenant un conditionnement de l'anticorps.

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