C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) C12N 5/16 (2006.01) C12P 21/08 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2595865
Abstract Immunoassay for Prion Disease This invention relates to the detection or assessment of prion disease in an individual by determining the binding of monoclonal antibodies specific for PrP to the surface of blood cells obtained from the individual. The binding of such antibodies is shown to correlate with the progression of prion disease. Methods of detecting or assessing prion disease are provided, along with kits and reagents.
La présente invention concerne la détection ou le dosage d'une maladie à prions chez un individu par mesure de la quantité d'anticorps monoclonaux spécifiques de PrP liés à la surface des cellules sanguines prélevées chez ledit individu. Il a été démontré que la liaison desdits anticorps est corrélée à la progression d'une maladie à prions. La présente invention décrit également des méthodes de détection ou de dosage de maladies à prions, ainsi que des kits et des réactifs pour ces méthodes.
Bujdoso Raymond
Thackray Alana
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Cambridge Enterprise Limited
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