Immunoassay method for bnp

G - Physics – 01 – N

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Details

G01N 33/74 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01) G01N 33/543 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2304263

The present invention is directed to an immunoassay specific for mammalian .gamma. -BNP derivatives, which uses the first antibody reactive with mammalian .alpha. -BNP and the second antibody reactive with mammalian prepro-BNP or .gamma. -BNP derivatives and not .alpha. -BNP, and at least one of the first and the second antibodies is optionally labeled detectably labeled or immobilized.

L'invention concerne un procédé de dosage immunologique spécifique des dérivés de gamma -BNP mammifère. Ce procédé consiste à utiliser un premier anticorps réagissant avec de l' alpha -BNP mammifère et un second anticorps réagissant avec des dérivés de gamma -BNP ou de préproBNP, mais pas avec de l' alpha -BNP. L'un de ces anticorps, au moins, a été marqué en vue d'être décelé ou a été posé sur une phase solide.

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