C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/18 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) A61K 49/00 (2006.01) C07D 215/52 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07K 16/44 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2164510
The present invention is directed to immunoassay reagents including specific antibodies to quinoline carboxylic acids, such as brequinar; novel quinoline carboxylic acid haptens useful as standards in immunoassays or for conjugating to large molecular weight carriers as immunogens or conjugating to detectable fluorescent moieties as tracer compounds. The present invention also relates to immunoassays for detecting quinoline carboxylic acids in clinical samples, and finally to kits containing said reagents.
L'invention porte sur des réatifs pour tests immunologiques comprenant des anticorps spécifiques des acides quinoléine-carboxyliques tels que le bréquinar; de nouveaux haptènes d'acides quinoléine-carboxyliques d'utilisation courante dans les tests immunologiques ou se liant à des supports de gros poids moléculaire pour former des immunogènes ou à des éléments fluorescents détectables pour former des traceurs. L'invention porte également sur des tests immunologiques de détection d'acides quinoléine-carboxyliques dans des prélèvements cliniques, et sur des trousses contenant lesdits réactifs.
Batt Douglas Guy
Galbraith William
Simon Paul Moore
Dimock Stratton Llp
Du Pont Pharmaceuticals Company
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