Immunoassays for .beta.2-microglobulin

Details Immunoassays for .beta.2-microglobulin Immunoassays for .beta.2-microglobulin

G - Physics

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G01N 33/566 (2006.01) G01N 33/543 (2006.01) G01N 33/58 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2478699

Immunoassays useful for detecting free .szlig.2-microglobulin in a sample containing .szlig.2-microglobulin/.szlig.2-microglobulin associated protein complexes are provided. Also provided are a sandwich immunoassay and a competition immunoassay for detecting free .szlig.2-microglobulin in a sample containing MHC monomers or MHC tetramers. Kits for performing such immunoassays also are provided.

L'invention concerne des dosages immunologiques utilisés pour la détection de la .beta.2-microglobuline dans un échantillon contenant des complexes de .beta.2-microglobuline et d'une protéine associée à une .beta.2-microglobuline. L'invention concerne également un dosage immunologique intercalé et un dosage immunologique de compétition permettant la détection de .beta.2-microglobuline libre dans un échantillon contenant des monomères MHC ou des tétramères MHC. L'invention concerne en outre des kits permettant d'effectuer les dosages immunologiques précités.

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