Immunoassays for specific determination of scca isoforms

Details Immunoassays for specific determination of scca isoforms Immunoassays for specific determination of scca isoforms

C - Chemistry, Metallurgy

07

K

C07K 16/30 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2498524

The present invention relates to monoclonal antibodies capable of distinguishing squamous cell cancer antigens, SCCA, in either free or complex bound forms, preferably antigens SCCA1 and SCCA2, as well as hybridomas recognizing such antibodies, method for diagnosing SCC, as well as diagnostic kits for detecting SCCAs.

L'invention concerne des anticorps monoclonaux capables de distinguer des antigènes du cancer des cellules squameuses, SCCA, sous des formes libres ou présentant des liaisons complexes, de préférence, des antigènes SCCA1 et SCCA2, ainsi que des hybridomes reconnaissant ces anticorps, une méthode servant à diagnostiquer SCC, et des trousses de diagnostic servant à détecter ces antigènes SCCA.

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