Immunoconjugate comprising an anti-egf receptor antibody and...

Details Immunoconjugate comprising an anti-egf receptor antibody and... Immunoconjugate comprising an anti-egf receptor antibody and...

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 38/20 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 14/52 (2006.01) C07K 14/54 (2006.01) C07K 16/30 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2158322

The invention relates to new immunoconjugates comprising of a monoclo-nal antibody or a fragment thereof specific for the human EGF-receptor molecule and a member of the chemokine family, preferably selected from the C-X-C family, e.g. Interleukin-8 (IL-8). The immunoconjugates induce cytotoxic and chemotactic activity and are suitable for a targeted tumor therapy.

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