Immunoconjugates for cancer diagnosis and therapy

Details Immunoconjugates for cancer diagnosis and therapy Immunoconjugates for cancer diagnosis and therapy

A - Human Necessities

61

K

167/129, 167/139

A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07K 16/30 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1336497

Immunoconjugates of an antibody to a 22 KD breast tumor associated antigen were prepared. Cytotoxic immunoconjugates such as gelonin-15A8 antibody conjugate are useful for treating proliferative cell diseases such as breast carcinoma and cervical carcinoma as well as other tumors which bear the 15A8 antigen. Detectably labeled compositions for diagnosis of such diseases are also disclosed.

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