Immunodiagnostic test for syphilis and other treponemal...

Details Immunodiagnostic test for syphilis and other treponemal... Immunodiagnostic test for syphilis and other treponemal...

G - Physics

01

N

167/41, 167/43,

G01N 33/571 (2006.01)

Patent

CA 1231892

IMMUNODIAGNOSTIC TEST FOR SYPHILIS AND OTHER TREPONEMAL INFECTIONS ABSTRACT OF THE DISCLOSURE A component for the rapid detection of anti- Treponemal antibodies or Treponemal immunogenic proteins adapted for use as a selective foundation material in standard immunoassays is provided. The component com- prises a quantity of fibronectin protein adhered to an insoluble support matrix. The fibronectin component provides a foundation material for the selective binding of Treponemal protein immunogens, either in the form of whole Treponemal organisms or solubilized protein frac- tions thereof. Incorporation of the fibronectin component and either anti-Treponemal antibody or Treponemal protein immungens into a standard immunoassay test-pack provides an immunological assay for the presence of respective complementary Treponemal protein immunogen or anti- Treponemal antibody in a biological sample.

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