Immunodominant human t-cell epitopes of hepatitis c virus

Details Immunodominant human t-cell epitopes of hepatitis c virus Immunodominant human t-cell epitopes of hepatitis c virus

C - Chemistry, Metallurgy

07

K

C07K 14/18 (2006.01) A61K 39/29 (2006.01) C07K 7/04 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2175692

The present invention relates to a polypeptide of about 8 to about 100 amino acids comprising or consisting of at least 8 contiguous amino acids selected from the core, and/or the E1, and/or E2, and/or the NS3 regions of the HCV polyprotein, with said contiguous amino acids containing a T-cell stimulating epitope.

L'invention concerne un polypeptide d'environ 8 à environ 100 aminoacides comprenant ou consistant en au moins 8 aminoacides contigus sélectionnés parmi les régions du noyau et/ou E1, et/ou E2, et/ou NS3 de la polyprotéine du VHC, lesdits aminoacides contigus contenant un épitope de stimulation des lymphocytes T.

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