Immunoenzymatic method for the determination of...

Details Immunoenzymatic method for the determination of... Immunoenzymatic method for the determination of...

G - Physics

01

N

167/37, 167/45

G01N 33/569 (2006.01) G01N 33/539 (2006.01)

Patent

CA 1331129

ABSTRACT OF THE DISCLOSURE An immunoenzymatic method for the detection of anti-Plasmodium falciparum-sporozoite antibodies in a sample of human blood, which operates, in homogeneous phase, and under suitable conditions, with a synthetic polypeptidic antigen (P), a synthetic antigen-enzyme (P-E) conjugate, wherein said antigen is capable of specifically reacting with the anti-Plasmodium falciparum-sporozoite antibodies (Ab) possibly present in the sample, and an inert substance capable of quantitatively precipitating the antibody- synthetic antigen-enzyme complex (Ab-P-E). The method, thanks to its specificity, sensibility, reproducibility and rapidity, is particularly useful in the epidemiological investigations into malaria and in the evaluation of the efficacy of an antimalarial vaccine.

597364

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