Immunogenic capsule composition for use as a vaccine...

A - Human Necessities – 61 – K

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A61K 39/02 (2006.01)

Patent

CA 2623400

An immunogenic composition, and method of using the composition, composed of a capsule polysaccharide polymer from one or more strains Campylobacter jejuni. The composition is either used alone or is conjugated to a carrier molecule, such as CRM197. An aspect of the invention is that the immunogenic composition induces an immune response without the induction of Gulliam Barre Syndrome.

L'invention concerne une composition immunogénique, et une méthode d'utilisation de celle-ci, composée d'un polymère de polysaccharide encapsulé obtenu d'une ou de plusieurs souches de Campylobacter jejuni. La composition est soit utilisée seule, soit conjuguée à une molécule de transport, telle que CRM197. L'invention concerne, dans un aspect, l'induction d'une réponse immune par la composition immunogénique sans induction du syndrome de Gulliam Barre.

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