Immunogenic complex, use, method of preparation thereof and...

Details Immunogenic complex, use, method of preparation thereof and... Immunogenic complex, use, method of preparation thereof and...

A - Human Necessities

61

K

A61K 39/385 (2006.01) A61K 39/02 (2006.01) A61K 39/112 (2006.01)

Patent

CA 2254084

The invention features an immunogenic complex, characterised in that it contains at least one oligo- or polysaccharide eptitope naturally present in bacteria, coupled with a carrier protein selected among the protein for binding with the human serumalbumin of Streptococcus, outer membrane proteins of gram-negative bacteria or fragments thereof. The invention also features vaccines containing such an immunogenic complex, and the method for preparing same.

La présente invention concerne un complexe immunogène, caractérisé en ce qu'il consiste en au moins un épitope oligo- ou polysaccharidique naturellement présent dans des bactéries, couplé à une protéine porteuse choisie parmi la protéine de liaison à la sérumalbumine humaine du Streptocoque, les protéines de membrane externe de bactérie gram negatif, ou leurs fragments. L'invention concerne également des vaccins comprenant un tel complexe immunogène, et procédé de préparation de ce complexe.

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