Immunogenic composition

Details Immunogenic composition Immunogenic composition

A - Human Necessities

61

K

A61K 39/095 (2006.01) A61K 39/102 (2006.01) A61K 39/116 (2006.01)

Patent

CA 2612957

The present application discloses an immunogenic composition comprising at least 2 different N. meningitidis capsular saccharides, wherein one or more is/are selected from a first group consisting of MenA, MenC, MenY and MenW which is/are conjugated to a protein carrier(s) wherein the saccharide:protein ratio (w/w) is between 1:2-1:5, and one or more different saccharides is/are selected from a second group consisting of MenA, MenC, MenY and MenW which is/are conjugated to a protein carrier(s) wherein the saccharide:protein ratio (w/w) is between 5:1-1:1.99.

L'invention concerne une composition immunogène comprenant deux saccharidescapsulaires N. meningitidis différents. Un ou plusieurs de ces saccharidessont choisis dans un premier groupe constitué de MenA, MenC, MenY et MenW, lesquels sont conjugués avec un ou plusieurs supports protéiques, le rapport saccharide/protéine (w/w) étant situé entre 1:2-1:5. Un ou plusieurs saccharides différents sont choisis dans un second groupe constitué de MenA, MenC, MenY et MenW qui sont conjugués avec un ou plusieurs supports protéiques, le rapport saccharide/protéine (w/w) étant situé entre 5:1-1:1.99.

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