Immunogenic composition and method of developing a vaccine...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 7/00 (2006.01) A61K 39/00 (2006.01) A61K 39/12 (2006.01) C12N 7/01 (2006.01) C12P 21/04 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2541492

The present invention relates to an immunogenic composition. More particularly, the present invention is a composition directed to eliciting an immune response to HIV fusion protein. The present invention contemplates three categories of embodiments: protein or protein fragments, messenger RNA, or DNA/RNA. DNA/RNA composition may be either naked or recombinant. The present invention further contemplates use with a variety of immune stimulants.

L'invention concerne une composition immunogène et, plus précisément, une composition visant à éliciter une réponse immunitaire à la protéine de fusion du VIH. L'invention concerne trois catégories de modes de réalisation: protéine ou fragments protéiques, ARN messager, ou ADN/ARN. Les compositions ADN/ARN peuvent être soit nues soit de recombinaison. L'invention concerne enfin l'utilisation avec une variété de stimulants immunitaires.

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