Immunogenic compositions comprising an antigen and a...

A - Human Necessities – 61 – K

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Details

A61K 39/155 (2006.01) A61K 39/135 (2006.01) A61K 39/39 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2436972

In summary of this disclosure, the present invention provides compositions and methods for enhancing an immune response to an antigen, in particular RSV antigens. The methods provide formulating immunogenic preparations to contain purified RSV M protein and at least one antigen from RSV or another antigen from a different infectious organism, or at least one immunogenic fragment thereof, in pre-selected amounts to elicit said enhanced immune response. Modifications are possible within the scope of the invention.

L'invention concerne des procédés et des compositions destinés à augmenter, chez un hôte, la réponse immune vis à vis d'un antigène. Une composition immunogène comprenant un antigène et une quantité de protéine M purifiée provenant du virus respiratoire syncytial est administrée, chez un hôte, en quantité sélectionnée afin d'obtenir une réponse immune améliorée contre cet antigène, cet hôte présentant une réponse immune spécifique préexistante contre la protéine M du virus respiratoire syncytial. L'antigène peut provenir du virus respiratoire syncytial.

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