C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) A61K 38/04 (2006.01) A61K 38/17 (2006.01)
Patent
CA 2597008
The present invention relates generally to the field of immunology and more particularly to molecules capable of stimulating a cellular immune response. More particularly, the present invention provides self-adjuvanting immunogenic molecules capable of stimulating an immune response to epitopes of a polypeptide irrespective of a subjects HLA type. The present invention further contemplates methods for the production and use of the self- adjuvanting immunogenic molecules and compositions comprising same useful in the vaccination of subjects against specific polypeptides.
La présente invention se rapporte de manière générale au domaine de l'immunologie et plus particulièrement aux molécules pouvant stimuler une réponse immunitaire cellulaire. Plus particulièrement, la présente invention concerne des molécules immunogènes auto-adjuvantes pouvant stimuler une réponse immunitaire contre des épitopes d'un polypeptide, quel que soit le type HLA du sujet. La présente invention concerne en outre des procédés de production et d'utilisation des molécules immunogènes auto-adjuvantes et des compositions les comprenant, pouvant être utilisées pour la vaccination de sujets contre des polypeptides spécifiques.
Jackson David C.
Zeng Weiguang
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Council Of The Queensland Institute Of Medical Research
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