Immunogenic pcpa polypeptides and uses thereof

Details Immunogenic pcpa polypeptides and uses thereof Immunogenic pcpa polypeptides and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/315 (2006.01) A61K 39/09 (2006.01)

Patent

CA 2660743

Provided herein are compositions and methods for eliciting an immune response against Streptococcus pneumoniae. More particularly, the compositions and methods relate to immunogenic polypeptides, including fragments of PcpA and variants thereof, and nucleic acids, vectors and transfected cells that encode or express the polypeptides. Methods of making and using the immunogenic polypeptides are also described.

La présente invention a pour objet des compositions et des procédés visant à provoquer une réponse immunitaire contre Streptococcus pneumoniae. Plus particulièrement, lesdits compositions et procédés concernent des polypeptides immunogéniques, dont notamment des fragments de PcpA et certaines de ses variantes et des acides nucléiques, des vecteurs et des cellules transfectées qui encodent ou expriment les polypeptides. L'invention a également pour objet des procédés d'obtention et d'utilisation des polypeptides immunogéniques.

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