Immunogenic peptides derived from the midkine protein, as an...

Details Immunogenic peptides derived from the midkine protein, as an... Immunogenic peptides derived from the midkine protein, as an...

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 14/475 (2006.01)

Patent

CA 2728459

A peptide derived from the Midkine protein, comprising at least one CD4+ T or CD8+ T epitope restricted by the HLA molecules predominant in the Caucasian population, or a polynucleotide encoding said peptide, as an anticancer vaccine or as a reagent for immunomonitoring of the cellular response against Midkine over the course of a cancer or of an anticancer treatment.

Peptide issu de la protéine Midkine comprenant au moins un épitope T CD4, ou T CD8, restreint aux molécules HLA prépondérantes dans la population caucasienne ou polynucléotide codant ledit peptide, comme vaccin anticancéreux ou comme réactif pour l'immunomonitoring de la réponse cellulaire contre la Midkine au cours d'un cancer ou d'un traitement anticancéreux.

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