Immunogenic peptides of prostate specific antigen

Details Immunogenic peptides of prostate specific antigen Immunogenic peptides of prostate specific antigen

C - Chemistry, Metallurgy

12

N

C12N 9/64 (2006.01) A61K 39/00 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 7/08 (2006.01) C07K 16/40 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2224149

Peptides derived from prostate specific antigen (PSA) that correspond to the immunodominant epitopes found in the native antigen are disclosed. These peptides were identified using a method that predicts continuous, immunodominant epitopes. Anti-PSA antibodies, methods for their production and their use in diagnostic assays also are disclosed.

Peptides dérivés de l'antigène spécifique de la prostate (PSA), qui correspondent aux épitopes immunodominants présents dans l'antigène natif. Ces peptides ont été identifiés au moyen d'un procédé qui prédit des épitopes immunodominants continus. Des anticorps dirigés contre les PSA, des procédés destinés à leur production ainsi que leur utilisation dans des dosages diagnostiques sont également décrits.

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