Immunogenicity of a vaccine by incorporation of a cytokine...

Details Immunogenicity of a vaccine by incorporation of a cytokine... Immunogenicity of a vaccine by incorporation of a cytokine...

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 38/20 (2006.01) A61K 39/155 (2006.01) A61K 39/385 (2006.01)

Patent

CA 2112508

TITLE: IMPROVED IMMUNOGENICITY OF A VACCINE BY INCORPORATION OF A CYTOKINE WITHIN AN IMMUNE-STIMULATING COMPLEX CONTAINING AN ANTIGEN ABSTRACT OF THE DISCLOSURE This disclosure describes a vaccine comprising an effective immunizing amount of an immune-stimulating complex which contains an antigen and a cytokine. The composition may also contain conventional adjuvants, preservatives and a pharmaceutically acceptable carrier. The disclosure further describes a unique method for enhancing or accelerating the immunogenicity of weak antigens by parenterally administering to a mammal an effective immunizing amount of the aforesaid vaccine.

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