Immunoglobulin bonding protein arrays in plant cells

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 21/04 (2006.01) C07K 16/00 (2006.01) C07K 16/12 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2377877

Arrays of immunoglobulin binding proteins in plants or plant cells are provided. Such arrays comprise plants or plant cells transformed with polynucleotides encoding multiple different immunoglobulin binding proteins, or polypeptide components thereof. Methods are further provided for genetic segregation of the transformation events such that each transformant in an array is capable of producing progeny capable of expressing one or more immunoglobulin binding proteins, including multi-subunit proteins.

La présente invention concerne des réseaux de protéines liant l'immunoglobuline dans des plantes ou des cellules végétales. Les réseaux de l'invention comprennent des plantes ou des cellules végétales transformées par des polynucléotides codant plusieurs protéines différentes liant l'immunoglobuline, ou par des composants polypeptidiques de ces derniers. L'invention se rapporte également à des procédés permettant une ségrégation génétique des événements de transformation telle que chaque transformant d'un réseau est capable de produire une descendance capable d'exprimer une ou plusieurs protéines liant l'immunoglobuline, y compris des protéines à sous-unités multiples.

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