A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 14/00 (2006.01)
Patent
CA 2620713
The present invention relates to immunoglobulin glycoprotein compositions having predominant N-glycan structures on an immunoglobulin glycoprotein which confer a specific effector function. Additionally, the present invention relates to pharmaceutical compositions comprising an antibody having a particular enriched N-glycan structure, wherein said N-glycan structure is selected from the group consisting of Man7GlcNAc2 and Man8G1cNAc2.
La présente invention concerne des compositions de glycoprotéine d'immunoglobuline présentant des structures N-glycane prédominantes sur une glycoprotéine d'immunoglobuline qui confèrent une fonction effectrice spécifique. En outre, la présente invention concerne des compositions pharmaceutiques comprenant un anticorps présentant une structure N-glycane enrichie particulière, cette structure N-glycane étant choisie dans le groupe constitué par Man7GlcNAc2 et Man8GlcNAc2.
Gerngross Tillman
Li Huijuan
Wildt Stefan
Gerngross Tillman
Glycofi Inc.
Gowling Lafleur Henderson Llp
Li Huijuan
Wildt Stefan
LandOfFree
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