Immunoglobulin conjugates

Details Immunoglobulin conjugates Immunoglobulin conjugates

A - Human Necessities

61

K

167/139

A61K 39/395 (2006.01) A61K 47/00 (2006.01) A61K 47/48 (2006.01) C07D 519/04 (2006.01)

Patent

CA 1210696

IMMUNOGLOBULIN CONJUGATES ABSTRACT OF THE INVENTION A conjugate comprising a vinca moiety convalently linked at the 4-position via a group of the formula -OCOXCO- where X represents a single chemical bond or an optionally substituted C1-10 chain, to an immunoglobulin or an immunoglobulin fragment. The conjugates are useful in the treatment of cancer.

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