Immunoglobulin fusion proteins

Details Immunoglobulin fusion proteins Immunoglobulin fusion proteins

C - Chemistry, Metallurgy

07

K

C07K 16/42 (2006.01) A61K 38/16 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2687377

Disclosed are fusion proteins comprising a biologically active molecule and an immunoglobulin (Ig) Fc domain which is linked to the biologically active molecule. The Fc domain is a hybrid human Fc domain of (i) IgG1, IgG2 or IgG4 or (ii) IgG4 and IgD. The hybrid Fc is useful as a carrier of biologically active molecules.

L'invention concerne des protéines de fusion comprenant une molécule biologiquement active et un domaine d'immunoglobuline (Ig) Fc qui est lié à cette dernière. Le domaine Fc est un domaine humain Fc hybride : de (i) IgG1, IgG2 ou IgG4, ou (ii) IgG4 et IgD. L'hybride Fc est utilisé comme excipient de molécules biologiquement actives.

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