Immunoglobulin g (igg) concentrate depleted of anti-a and...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61P 43/00 (2006.01) C07K 1/36 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2634997

The present invention relates to an immunoglobulin G concentrate for therapeutic use, in which the respective contents of anti-A and anti-B antibodies are in accordance with a negative result in the in vitro indirect Coombs test. This IgG concentrate also has a polyreactive IgG content of between 0.01% and 0.1%, in particular between 0.07% and 0.1%, relative to the total content of IgG.

La présente invention concerne un concentré d' immunoglobulines G à usage thérapeutique dans lequel les teneurs respectives en anticorps anti-A et anti-B sont conformes à un résultat négatif au test de Coombs indirect in vitro. Ce concentré d'IgG présente en outre une teneur d'IgG polyréactives comprise entre 0,01% et 0,1%, en particulier entre 0,07 et 0,1%, par rapport à la teneur totale en IgG.

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