Immunoglobulin infusion in xenotransplantation

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) C07K 16/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2161349

Intravascular introduction of pooled immunoglobulin is employed prior to xenotransplantation to extend the effective lifetime of the donor organ. In particular, intravenous administration of concentrated immunoglobulin for intravenous use (IVIg) by itself, or in combination with immunosuppressive agents is used to enhance the survival time of xenografts.

L'introduction intraveineuse d'immunoglobulines provenant de plusieurs donneurs est employée avant une hétérogreffe pour prolonger la durée de vie efficace de l'organe du donneur. En particulier, l'administration intraveineuse d'immunoglobulines concentrées à usage intraveineux (IVIg) seules ou en combinaison avec des agents immunosuppresseurs est utilisée pour améliorer le temps de survie de hétérogreffes.

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