Immunoglobulin purification

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 39/395 (2006.01) C07K 1/18 (2006.01) C07K 16/06 (2006.01)

Patent

CA 2745707

The current invention reports a method for purifying an immunoglobulin, wherein the method comprises applying an aqueous, buffered solution comprising an immunoglobulin in monomeric, in aggregated, and in fragmented form to an anion exchange chromatography material under conditions whereby the immunoglobulin in monomeric form does not bind to the anion exchange material, and recovering the immunoglobulin in monomeric form in the flow-through from the anion exchange chromatography material, whereby the buffered aqueous solution has a pH value of from 8.0 to 8.5. In one embodiment the anion exchange chromatography material is a membrane anion exchange chromatography material.

La présente invention porte sur un procédé pour purifier une immunoglobuline, le procédé comprenant l'application d'une solution tamponnée, aqueuse, comprenant une immunoglobuline sous forme monomère, agrégée et fragmentée sur un matériau de chromatographie échangeuse d'anions dans des conditions où l'immunoglobuline sous forme monomère ne se lie pas au matériau d'échange d'anions, et la récupération de l'immunoglobuline sous forme monomère dans l'écoulement traversant à partir du matériau de chromatographie échangeuse d'anions, la solution aqueuse tamponnée ayant une valeur de pH de 8,0 à 8,5. Dans un mode de réalisation, le matériau de chromatographie échangeuse d'anions est un matériau de chromatographie échangeuse d'anions membranaire.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Immunoglobulin purification does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Immunoglobulin purification, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunoglobulin purification will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1763543

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.