Immunoglobulin purification

Details Immunoglobulin purification Immunoglobulin purification

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) C07K 1/16 (2006.01) C07K 1/18 (2006.01)

Patent

CA 2687837

The current invention reports a method for purifying an immunoglobulin, wherein the method comprises applying an aqueous, buffered solution comprising an immunoglobulin in monomeric and in aggregated form to a cation exchange material under conditions whereby the immunoglobulin in monomeric form does not bind to the cation exchange material, and recovering the immunoglobulin in monomeric form from the solution after the contact with the cation exchange material.

La présente invention porte sur un procédé pour purifier une immunoglobuline. Ce procédé comporte l'application d'une solution tamponnée, aqueuse, comportant une immunoglobuline sous forme monomère et agrégée, à une matière d'échange de cations dans des conditions dans lesquelles l'immunoglobuline sous forme monomère ne se lie pas à la matière d'échange de cations, et la récupération de l'immunoglobuline sous forme monomère de la solution après le contact avec la matière d'échange de cations.

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