Immunoglobulin variants with altered binding to protein a

Details Immunoglobulin variants with altered binding to protein a Immunoglobulin variants with altered binding to protein a

C - Chemistry, Metallurgy

07

K

C07K 16/12 (2006.01) A61K 39/395 (2006.01) A61K 39/40 (2006.01) C07K 14/31 (2006.01)

Patent

CA 2746330

Variant immunoglobulins with one or more amino acid modifications in the VH region that have al-tered binding to Staphylococcus aureus protein A, and methods of using the same are provided.

Variantes d'immunoglobulines comportant une ou plusieurs modifications d'acides aminés dans la région VH, lesdites variantes présentant des propriétés de liaison altérées vis-à-vis de la protéine A de Staphylococcus aureus, et leurs méthodes d'application.

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