C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/22 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01)
Patent
CA 2573541
The present invention relates to immunoglobulin glycoprotein compositions having predominant N-glycan structures on an immunoglobulin glycoprotein which confer a specific effector function. Additionally, the present invention relates to pharmaceutical compositions comprising an antibody having a particular enriched N-glycan structure, wherein said N-glycan structure is Man3GlcNAc2.
La présente invention concerne des compositions glycoprotéiniques d'immunoglobulines présentant des structures <I>N</I>-glycanniques principales sur une glycoprotéine d'immunoglobuline qui confère une fonction effectrice spécifique. En outre, la présente invention concerne des compositions pharmaceutiques comprenant un anticorps présentant une structure <I>N</I>-glycannique enrichie particulière, ladite structure <I>N</I>-glycannique étant de type Man3GlcNAc2.
Gerngross Tillman U.
Li Huijuan
Wildt Stefan
Glycofi Inc.
Gowling Lafleur Henderson Llp
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