Immunohistochemical methods

Details Immunohistochemical methods Immunohistochemical methods

G - Physics

01

N

G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2544855

The present invention relates to immunohistochemical methods to identify biomarkers. This invention relates to the use of phospho-ERK (pERK) levels in tumor cells as a biomarker for a Raf kinase inhibitor. The invention also provides methods and compositions for diagnostic assays for detecting cancer.

La présente invention concerne des méthodes immunohistochimiques d'identification de biomarqueurs. Elle porte sur l'utilisation de niveaux phospho-ERK (pERK) dans des cellules tumorales comme biomarqueurs de l'inhibiteur de la Raf kinase. L'invention concerne également des méthodes et des compositions pour essais diagnostiques de détection du cancer.

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