A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 9/127 (2006.01)
Patent
CA 2605560
An immunoliposome composition comprised of liposomes bearing a ligand for targeting to cells expressing a growth factor receptor, such as HER2, is described. Binding of the immunoliposome to HER2-expressing cells results in internalization of the immunoliposome for cytoplasmic delivery of an entrapped drug.
L'invention concerne une composition d'immunoliposomes constituée de liposomes portant un ligand de ciblage de cellules exprimant un récepteur de facteur de croissance, tel que HER2. La liaison de l'immunoliposome aux cellules exprimant HER2 entraîne l'internalisation de l'immunoliposome pour la libération cytoplasmique d'un médicament piégé.
Abra Robert
Guo Luke
Hjortsvang Kristen
Huang Anthony
Kelley Laura
Alza Corporation
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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