Immunological composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/39 (2006.01)

Patent

CA 2734654

The present invention relates to immunological compositions comprising sulpholipo-cyclodextrin (SL-CD) and, saponin or Quil A, and optionally at least one antigen The invention relates to methods and immunological compositions comprising at least one antigen, which may be a veterinary antigen The veterinary antigen in the methods and immunological compositions of the invention may be a bovine antigen The invention relates to methods and immunological compositions comprising bovine ephemeral fever virus (BEFV), bovine herpesvirus 1(IBR) or bluetongue virus (BTV) The invention comprises methods for eliciting an immune response against BEFV, IBR, or BTV in an animal, which comprises administering to the animal a composition of the invention In the invention, particularly the immune response is a protective immune response The invention comprises a method for preparing an immunological composition comprising adding Quil A to a virus

La présente invention concerne des compositions immunologiques comprenant de la sulpholipo-cyclodextrine (SL-CD) et de la saponine ou du Quil A, et éventuellement au moins un antigène. Linvention porte en outre sur des méthodes et des compositions immunologiques comprenant au moins un antigène, qui peut être un antigène à usage vétérinaire. Ledit antigène à usage vétérinaire selon les méthodes et les compositions immunologiques de linvention peut être un antigène bovin. Linvention a également trait à des méthodes et à des compositions immunologiques comprenant le virus de la fièvre éphémère bovine (BEFV), le virus de lherpès bovin 1 (IBR) ou le virus de la fièvre catarrhale du mouton (BTV). Linvention porte sur des méthodes permettant de déclencher une réponse immunitaire contre le BEFV, lIBR ou le BTV chez un animal, lesquelles méthodes comprennent ladministration dune composition de linvention audit animal. Dans la présente invention, la réponse immunitaire est, en particulier, une réponse immunitaire protectrice. Linvention concerne également un procédé de préparation dune composition immunologique comprenant lajout de Quil A à un virus.

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