Immunological conjugates of ompc and hiv-specific selected...

Details Immunological conjugates of ompc and hiv-specific selected... Immunological conjugates of ompc and hiv-specific selected...

C - Chemistry, Metallurgy

12

N

C12N 15/64 (2006.01) A61K 39/095 (2006.01) A61K 39/21 (2006.01) A61K 39/295 (2006.01) A61K 39/385 (2006.01) C07K 7/08 (2006.01) C07K 14/155 (2006.01) C07K 14/16 (2006.01) C07K 14/22 (2006.01) C07K 16/10 (2006.01) C07K 17/06 (2006.01) C12N 7/04 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2139517

Immunological conjugates of HIV-specific selected principal neutralization epitopes are prepared. These epitopes bind a broadly neutralizing human monoclonal antibody specific for the HIV principal neutralization epitope(s) and are identified from oligopeptide epitope libraries. The conjugates are useful for vaccination against AIDS or ARC, as well as in the production of other HIV-specific broadly neutralizing antibodies for passive immunity against AIDS or ARC.

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