Immunological methods of component selection and recovery

Details Immunological methods of component selection and recovery Immunological methods of component selection and recovery

G - Physics

01

N

G01N 33/538 (2006.01) C07K 1/22 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/554 (2006.01)

Patent

CA 2261273

The invention involves an immunological method of separating specifically- targeted cells or molecular structures from a mixed population under conditions which minimize damage to the cellular structure or the molecular integrity. The method is based upon the specific interaction of a label and an antibody directed against the label and the ability of a competitor to inhibit the interaction between the label and the antibody.

L'invention se rapporte à un procédé immunologique de séparation de cellules ou de structures moléculaires, ciblées de manière spécifique, et présentes dans une population mélangée, ladite séparation ayant lieu dans des conditions qui minimisent les dégâts occasionnés à la structure cellulaire ou à l'intégrité moléculaire. Ledit procédé est fondé sur une interaction spécifique d'un marqueur et d'un anticorps dirigé contre ledit marqueur et sur la capacité d'un concurrent à inhiber l'interaction entre le marqueur et l'anticorps.

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