Immunological test for the detection of autoantibodies...

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G01N 33/68 (2006.01) C12N 9/90 (2006.01)

Patent

CA 2741755

The present invention discloses an immunological test for the detection and specific determination of autoantibodies against testicular antigens which are associated with inflammation-related fertility disorders of male mammals in a biological sample of a male mammal, in particular the detection of testicular ER-60 autoantibodies and/or transferrin autoantibodies. The immunological test is utilized to detect the presence of immunologically- caused and infection-related infertility in male mammals, particularly in humans.

La présente invention concerne un test immunologique destiné à détecter et à identifier spécifiquement, dans un échantillon biologique d'un mammifère mâle, des auto-anticorps dirigés contre des antigènes testiculaires qui accompagnent des troubles de la fertilité d'origine inflammatoire chez des mammifères mâles, en particulier pour la détection d'auto-anticorps testiculaires anti-ER-60 et/ou d'auto-anticorps testiculaires anti-transferrine. Le test immunologique est utilisé pour déterminer l'existence d'une infertilité d'origine immunologique et infectieuse chez des mammifères mâles, en particulier chez l'homme.

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