C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/70 (2006.01) A61K 39/23 (2006.01) C07K 1/14 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/015 (2006.01) C12N 9/10 (2006.01) C12N 9/38 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2075366
Immunologically active peptides or polypeptides with a partial amino-acid sequence of the capsid proteins VP1 and VP2 of parvovirus B19 which permit tests to be carried out at low cost, sensitively and specifically for the determination of antibodies against human parvovirus B19 are made available. Short peptide sequences which, employed as antigen, serve to identify anti-B19 IgG- positive sera are identified. Furthermore, the production of these peptides using genetic engineering measures is disclosed. Other antigens which are produced by genetic engineering and which can be stably produced in a high yield in E.coli and subsequently purified therefrom are used as additional antigens for IgG detection. Finally, a set of antigens permits tests to be carried out to determine IgM antibodies against the virus. In addition, the components, produced by genetic engineering, of the surface proteins represent substances which can be used for prophylactic immunisation.
Motz Manfred
Soutschek Erwin
Mikrogen Molekularbiologische Entwicklungs- Gmbh
Moffat & Co.
LandOfFree
Immunologically active peptides or polypeptides from the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunologically active peptides or polypeptides from the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunologically active peptides or polypeptides from the... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2044679