Immunologically active synthetic peptides useful for...

Details Immunologically active synthetic peptides useful for... Immunologically active synthetic peptides useful for...

C - Chemistry, Metallurgy

07

K

167/129, 167/37,

C07K 7/04 (2006.01) A61K 39/00 (2006.01) C07K 14/445 (2006.01) C07K 16/20 (2006.01)

Patent

CA 1316632

ABSTRACT OF THE DISCLOSURE: Synthetic peptides consisting of at least two consecutive repeating units of the sequence (Ala-Asn-Asn-Pro) are powerful immunogens in experimental animals. The antibodies which form recognise both the synthetic peptides and the immunodominant epitope of the circumsporozoitic peptide of Plasmodium falciparum. These peptides, obtainable in pure form, are particularly useful for preparing antimalarial vaccines and diagnostic kits for the determination of malarial affections.

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