Immunomodulating compositions and their use

Details Immunomodulating compositions and their use Immunomodulating compositions and their use

A - Human Necessities

61

K

167/129

A61K 39/00 (2006.01)

Patent

CA 1301064

59 24556/IMUL-1-3 IMMUNOMODULATING COMPOSITIONS AND THEIR USE ABSTRACT OF THE DISCLOSURE Novel methods or compositions are provided for modulating the immune system, so as to be able to se- lectively stimulate or inactivate lymphocytes in rela- tion to a particular transplantation antigen context. Particularly, mixtures may be employed associated with the more common transplantation antigens of a host pop- ulation. In this manner, a large number of people can be treated, for example, by immunization, stimulation of particular T-cells or B-cells in relation to a path- ogenic invasion or other aberrant state, e.g. neopla- sia, treatment of autoimmine diseases, and the like. Particularly, the compositions may involve an oligopep- tide involving as a first region a consensus sequence and an epitope or the first region may be joined to a second region comprising an antibody target sequence which is capable of competing with an epitopic site of an antigen of interest.

541064

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