Immunomodulating oxopyrrazolocinnolines as cd80 inhibitors

Details Immunomodulating oxopyrrazolocinnolines as cd80 inhibitors Immunomodulating oxopyrrazolocinnolines as cd80 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/5025 (2006.01) A61P 3/10 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 37/00 (2006.01) C07D 231/00 (2006.01) C07D 241/00 (2006.01)

Patent

CA 2576256

N-(l-Aza-bicyclo[2.2.2]oct-3-yI)-4-(6,9-difluoro-3-oxo-1,3-dihydro- pyrazolo[4,3clcinnolin-2-yI)-benzamide is a CD80 antagonist, useful in the treatment of diseases which benefit from immuno-inhibition.

La présente invention concerne la N-(l-Aza-bicyclo[2.2.2]oct-3-yI)-4-(6,9-difluoro-3-oxo-1,3-dihydro-pyrazolo[4,3clcinnolin-2-yI)-benzamide qui est un antagoniste du CD80, utile dans le traitement des maladies bénéficiant de l~immuno-inhibition.

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