Immunomodulatory constructs and their uses

Details Immunomodulatory constructs and their uses Immunomodulatory constructs and their uses

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 35/74 (2006.01) A61K 39/00 (2006.01) A61K 39/09 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) C07H 19/00 (2006.01) C07K 14/00 (2006.01) C07K 14/315 (2006.01) C07K 16/12 (2006.01) C12N 1/20 (2006.01) C12N 15/31 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2488234

The invention relates to immunomodulators. In particular the invention relates to specific immunomodulators based on the superantigen SMEZ-2 and more particularly based on mutants of the superantigen SMEZ-2, which are adapted to target antigen-presenting-cells for the purpose of enhancing or suppressing a host immune response.

La présente invention concerne des immunomodulateurs. L'invention concerne en particulier des immunomodulateurs spécifiques basés sur le superantigène SMEZ-2 et plus particulièrement basé sur des mutants du superantigène SMEZ-2, qui conviennent aux cellules de présentation de l'antigène cibles dans le but d'améliorer ou de supprimer une réponse immunitaire chez l'hôte.

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