Immunomodulatory constructs and their uses

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) A61P 37/02 (2006.01) C07K 14/00 (2006.01) C07K 14/31 (2006.01) C07K 14/315 (2006.01) C07K 19/00 (2006.01) C12N 15/31 (2006.01)

Patent

CA 2436856

An immunomodulator which comprises an antigen-presenting-cell (APC) targeting molecule coupled to an immunomodulatory antigen, wherein said APC-targeting molecule mimics a superantigen but does not include a fully functional T-cell receptor binding site.

L'invention concerne un immunomodulateur, lequel comprend une molécule de ciblage d'une cellule présentatrice d'antigène (APC), couplée à un antigène immunomodulateur, ladite molécule de ciblage imitant un superantigène mais ne possédant pas un site de liaison de récepteur de lymphocytes T totalement fonctionnel.

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