Immunomodulatory extracts from lactobacillus bacteria and...

C - Chemistry – Metallurgy – 12 – N

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C12N 1/20 (2006.01) A61K 35/74 (2006.01) A61P 29/00 (2006.01) A61P 37/04 (2006.01) C12P 1/04 (2006.01) C12N 1/06 (2006.01)

Patent

CA 2733249

The present invention includes extracts from Lactobacillus bacteria, which may produce immunomodulatory effects in subjects. Embodiments of the invention may be used, for example, as nutraceuticals or pharmaceuticals for treatment of diseases or as adjuvants in medical treatment, such as those related to an imbalance of the production of anti-inflammatory or proinflammatory cytokines. Conditions for which extracts of the invention may be useful include infections, allergies, autoimmunity disorders, and inflammation, or as adjuvants providing healthful benefits in subjects. The invention also includes, inter alia, methods of making and using such extracts. The invention also relates to particular strains of Lactobacillus bacteria.

La présente invention concerne des extraits de bactéries Lactobacillus, qui peuvent produire des effets immunomodulateurs chez des sujets. Des modes de réalisation de linvention peuvent être utilisés, par exemple, en tant quagents nutraceutiques ou pharmaceutiques pour le traitement de maladies ou en tant quadjuvants dans un traitement médical, tel que ceux associés à un déséquilibre de la production de cytokines anti-inflammatoires ou pro-inflammatoires. Les affections pour lesquelles les extraits de linvention peuvent être utiles comprennent des infections, des allergies, des troubles auto-immuns, et linflammation, ou en tant quadjuvants produisant des bénéfices pour la santé chez des sujets. Linvention comprend en outre, entre autres, des procédés de fabrication et dutilisation de tels extraits. Linvention concerne en outre des souches particulières de bactéries Lactobacillus.

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