Immunomodulatory polynucleotides in treatment of an...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 35/00 (2006.01) A61K 45/06 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2398756

The present invention features methods for treatment or prevention of infection by intracellular pathogens (e.g., Mycobacterium species) by administration of an immunomodulatory nucleic acid molecule. In one embodiment, immunomodulatory nucleic acid molecule are administered in combination with another anti-pathogenic agent to provide a synergistic anti- pathogenic effect.

L'invention concerne des méthodes de traitement ou de prévention d'infection par des pathogènes intracellulaires (p. ex. genreMycobacterium), par l'administration d'une molécule d'acide nucléique immunomodulatrice. Dans une forme de réalisation, la molécule d'acide nucléique immunomodulatrice est administrée en combinaison avec un autre agent antipathogène pour obtenir un effet antipathogène synergique.

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