C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/08 (2006.01)
Patent
CA 2615391
The present invention encompasses methods and compositions for generating an isolated adipose tissue-derived stromal cell exhibiting a low level of immunogenicity. The present invention encompasses methods and compositions for reducing an immune response associated with transplantation by administering the recipient with an amount of adipose tissue-derived stromal cells effective to reduce or inhibit host rejection and/or host versus graft disease.
L'invention concerne des méthodes et des compositions permettant de générer une cellule stromale isolée dérivée de tissus adipeux présentant un faible niveau d'immunogénicité. L'invention concerne également des méthodes et des compositions permettant de réduire une réaction immunitaire associée à la transplantation par administration au destinataire d'une dose efficace de cellules stromales dérivées de tissus adipeux pour réduire ou inhiber un rejet par l'hôte et/ou une maladie hôte-greffon.
Gimble Jeffrey M.
Mcintosh Kevin R.
Mitchell II James B.
Board Of Supervisors Of Louisiana State University And Agricultu
Borden Ladner Gervais Llp
Cognate Therapeutics Inc.
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