Immunophilin ligands and methods for modulating immunophilin...

Details Immunophilin ligands and methods for modulating immunophilin... Immunophilin ligands and methods for modulating immunophilin...

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) C12N 5/079 (2010.01) A61K 31/436 (2006.01) A61K 38/17 (2006.01) A61K 38/52 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C07K 16/44 (2006.01) C12N 9/90 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2676613

Immunophilin ligands and their uses as modulators of calcium channel activity are disclosed. Screening, therapeutic and prophylactic methods for conditions associated with calcium channel dysfunction, e.g., neurodegenerative and cardiovascular disorders, are also disclosed.

L'invention concerne des ligands d'immunophilines et leurs utilisations en tant que modulateurs de l'activité des canaux calciques. L'invention concerne également des procédés de dépistage, de thérapie et de prophylaxie de conditions associées à un dysfonctionnement des canaux calciques, par exemple des troubles neurodégénératifs et cardiovasculaires.

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