Immunopotentiating inosine monophosphate 5'-nucleotidase...

Details Immunopotentiating inosine monophosphate 5'-nucleotidase... Immunopotentiating inosine monophosphate 5'-nucleotidase...

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 31/7076 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2675757

A method of making inosine-5'-monophosphate and its derivatives resistant to 5'-nucleotidase by chemically modifying inosine-5'-monophosphate to formula (I) wherein R is selected from the group consisting of an alkyl, alkoxy and secondary amino compounds whereby inosine-5'-monophosphate biological activity is retained in vivo.

Divulgation d'une méthode pour produire de l'inosine-5'-monophosphate et ses dérivés résistant à la 5'-nucléotidase en modifiant chimiquement l'inosine-5'-monophosphate de formule (I), dans laquelle R est choisi parmi le groupe constitué de groupes alkyl, alcoxy et amine secondaire. Grâce à cette méthode l'activité biologique de l'inosine-5'-monophosphate est conservée in vivo.

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