C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/28 (2006.01) C07K 7/06 (2006.01) C07K 14/47 (2006.01) C07K 14/62 (2006.01) C12N 9/88 (2006.01) G01N 33/564 (2006.01) G01N 33/74 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2213301
The present invention relates generally to molecules such as peptides, polypeptides and proteins which interact immunologically with antibodies or T-cells in subjects having pre-clinical or clinical Insulin- Dependent Diabetes Mellitus (IDDM). These molecules are preferentially immunoreactive to T-cells in subjects having pre-clinical or clinical IDDM and are useful in the development of diagnostic, therapeutic and prophylactic agents for IDDM.
Cette invention traite, d'une manière générale, de molécules telles que des peptides, des polypeptides et des protéines qui interagissent de manière immunologique avec des anticorps ou des cellules thymo-dépendantes chez des sujets atteints du diabète sucré insulinodépendant (IDDM) préclinique ou clinique. Ces molécules qui sont, de préférence, immunoréactives par rapport aux cellules thymo-dépendantes chez des sujets atteints du diabète sucré insulinodépendant (IDDM) préclinique ou clinique, s'avèrent utiles dans l'établissement d'un diagnostic, la mise au point d'agents thérapeutiques et prophylactiques pour l'IDDM.
Harrison Leonard
Honeyman Margo
Lew Andrew
Rudy George
Amrad Operations Pty. Ltd.
Fetherstonhaugh & Co.
The Walter And Eliza Hall Institute Of Medical Research
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